h a l f b a k e r yPoof of concept
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1100 toothaches removed per each single iontophoretic electric toothbrush:
A 2-3 cent alibaba toothbrush gets rid of toothaches because it contains peptides delivered iontophoretically that anesthetize the tooth.
I think people are better off getting cavities filled at an actual dentist. For
some people at the developing world that may not be an easy option. These people could get or borrow an iontophoretic (electricity pushes drugs through gums to tooth root area) toothbrush that will anesthetize a tooth for 3-6 months or longer with one application
The peptide could be a glutamate receptor antagonist/blocker, or an opiate peptide.
Can be used 1100 times (contains 2-1100 micrograms of peptide)
oxytoxin, a 7-8 amino acid peptide at $300-500/kilogram
https://www.alibaba...itle.28822f8fUbuLVk
[beanangel, Jan 14 2021]
1 Joan Savage & Ken Morris - The Old Bazaar in Cairo
https://www.youtube...watch?v=crzmJJj3P-o
[Voice, Jan 14 2021]
[link]
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[-] Anesthetizing a bad tooth will not fix what’s
wrong with it. Long term use of a contact
anesthetic is likely to cause other problems. And
even if you found a magic peptide that provides
the effect you want - and electrify a toothbrush to
make an “iontophoretic” effect - it’s no longer “2-
3 cent” item. |
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I regret I have but one fishbone for this idea, as it
so richly deserves more. |
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[KDF] that's why I suggested it might be of more use at the developing world (fewer dentists to go to) |
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Also, the actual alibaba ingredients at 2-3 cents: Toothbrush 1 cent; peptide 1/10th of a cent; 1000milliamp hour battery 1 cent; worst case for alibaba is the 8 cent cat toy laserpointer (batteries, plastic tube, semiconductor) |
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You are SO full of sh ... |
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... Shine your buttons with Brasso, it’s only three
ha'pence a tin... |
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... which may be cheaper and more realistic than
an unnamed peptide that will only cost 1/10 of a
cents for a six month treatment, and can numb
the gums without other ill effects. |
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... You can buy it or whip it from Woolworths, but I
don't think they've got any in! |
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Look on the bright side, [kdf]; one day, he may not only come up with an idea that's practical, but one which uses components that Alibaba actually pays him to take away... at which point he'll implode, or form a singularity, or something else equally drastic and entertaining. |
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" ...Sand bags, wind bags, camels with a hump,
Fat girls, thin girls, some a little plump,
Slave girls sold here, fifty bob a lump,
In the old bazaar in Cairo ..."
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Thanks, haven't heard that one since I was a kid.
Now I’ll hum it and wife will be mad at me for
getting the tune stuck in her head as well. |
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[KDF] the iontophoretic toothache removing toothbrush is a thing that I actually think would work. iontophoresis (10V, 30 milliamps, 10 minutes) is a medical treatment for sweaty palms. I use that to base the batteries on. |
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I read 700 picograms of an opiate peptide will anesthetize an entire rat; so if the rat weighs 400 grams, then 1 nanogram will cover 100 separate doses of 4g mass of gum/tooth. 1 milligram will cover 100,000 doses. If the peptide is $100/gram then that is 10c/mg, or about a millionth of a cent a dose. |
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Notably though, the anesthetic system would migrate in 200 gradually rediffusing doses per tooth electrification, so that is 5,000 doses per medicated iontophoretic toothbrush. |
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oxytocin, an different peptide on alibaba is 30 cents a gram (link), so even if a different better peptide is used it is superaffordable. |
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Summary: Use a toothbrush to anaesthetise your
teeth. |
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