Sexually transmitted infections (STI/STD), are, I read, associated with microabrasions and microtears at the genitals and anus. Putting wound healing chemicals in sexual lubricants, cerivical rings (like Nuvaring), condoms, and what I call a vaginal decal is possible. Published material found 30-80%
to tripled wound healing effectiveness with Various herbal extracts, yeast extracts, and formal drugs, so the healing part is published as working [links].
So, basically, you put the wound healing chemical in the cervical ring (nuvaring) or sex lubricant, and the person might be 30-80% - 3 times less likely to get or transmit sexually transmitted infections.
As a new technology so this idea stays up, Here is the vaginal decal:
A slick, self-wetting biodegradeable polymer decal, with something like instant-set surgical glue on the peel-off back is produced (alibaba similars 2/1000 of 1 cent). The woman or girl places the decal, which could be as small as 3 mm times 3 mm at the interior of her vagina, something like hand inserting an OB(tm) tampon. The upper surface is a polymer or gel that diffuses healing materials, other varied purpose chemicals or materials, or varied purpose drugs into the vaginal mucous.
Surgical glue can last about 3 months and the decal can diffuse very high dose potency drugs (Some I have read about are active at picograms or even femtograms) even though the decal itself might have a 1-4mg mass.
The advantage of the decal is that it could deter STIs for a months. There is also an ionophoretic keratin reactive version of a vaginal decal that could confer multiple years of abrasion healing and minimization of sexually tranmistted infecion (STI/STD) transmission (See *note)
The healing component:
The [link] note that ethanolic yeast extract triples wound healing velocity. As a different extract perhaps the yeast extracts could be dissolved not in ethanol, but in an alcohol with more atoms like erithritol, sorbitol, or even an L-sugar alcohol that vaginal bacteria cannot eat.
There is another study [link] where they found the active ingredients of ethanolic yeast extract (peptides, which I think may have became cosmetic beauty peptides at commercial products) These extracts are 6000 times more potent than the yeast extract, some, I think, are widely used as beauty peptides in cosmetics.
Noting beauty peptides = published healing peptides (GHK-Cu is one). Sociocultural acceptance of Named ingredients has already occurred. Just adding that ingredient to condom lubricants, sexual lubricants, vaginal decals, cervical rings (Nuvaring). and, with engineering, tampons could result in 30-80% - 3 times less unhealed abrasion at the vagina (and anus) and reduce sexual transmission of infections.
The Tampon that leaves an all month healing residue is very much like the vaginal decal. The medicated tampon's advantage is that you don't have to think about it, you just use "Satyfresh -Active" every month automatically.
The advantage of the decal is that it could deter STIs for a months. There is also an ionophoretic keratin reactive version that could confer multiple years of minimization of sexually tranmistted infecion (STI/STD) transmission (See *note)
I think the medicated tampon is WKTE, so this is a just a version. A polymer melts-at-vagina-temperatures thing, coating or halftone dot screen on the tampon, loaded with healing chemicals that comes off on insertion has surgical glue that coats the dots or dust attaches it to the vaginal walls.
This is likely 100 micrograms-4 mg of "glue dust/dots" that get transferred to the sides of the vagina. The glue dots then persist a month, and are renewed with sequential monthly tampon use. As previously mentioned .1-4 mg is more than sufficient as some healing chemicals are active at 3-5 orders of magnitude less mass.
Other wound healing chemicals that may have already become socioculturally acceptable are curcurmin (30-100% healing effects). Very many healing factors, peptides and proteins have been published. A few that I noticed are Trefoil TFF peptide[link], NGF, VEGF.
As a fast track to sociocultural acceptance, Other yeast species' extracts besides those from Saccharomyces cerevisiae could be tried. Encouragingly, "probiotic extracts", which I think means they grow the probiotic bacteria and then extract stuff from it are already in cosmetics [link]. Countless probiotic bacteria are there to be tested for beneficial medical effects, and have the advantage of already being parts of unlicensed products.
So, sexual and genital contact materials that promote wound healing reduce the spread of STIs and are about 1-2/100th of 1 cent to make. They are a technology, and it is beneficial to make them.
An alibaba cost estimate of 10 mg $6/gram beauty=healing peptide (GHK-Cu), and 10 milligrams of surgical glue [link] $1.149/gram is about 7.2/1000ths of a cent, or 1/100th of a cent costincrease per medicated tampon.
*Note: If you like, you can really do it right and get 5 or even 10 years of vaginal or anal wound healing out of one application. The technology works like this:
A drug-coated soft polymer tube is inserted into the vagina or anus. Iontophoresis, which can deliver 25 mg of active ingredient per (cm^2) in less than 30 minutes to a depth of 1-3 cm, transports the very high dose potency drugs (fluorinated ethynylized healing peptides; computer modeled and redesigned healing peptides, ethynlfluorocurcumin).
The durability and diffusivity scope of the healing drugs is increased by attaching them to a keratin (or likely other connective tissue) reactive moiety that does the micheal reaction, molecularly attaching them to tissue. To emphasize this is easier than it sounds, just think of it as electrophoresisizing a kind of transparent Henna. Henna already lasts a month,and when a sponge is completely soaked in it, rather than a surface painted, it likely lasts, and diffuses out, much longer.
The iontophoretic area could be as much as say the full surface area of the inside of the vaginal canal, and say 12 inches of anal depth and circumferance.
These high dose potency healing drugs are in a form that causes them to diffuse back out towards the mucousa at a 1 microgram/24 hours velocity; so 1 year is about 1/3 milligram of active drug utilized. Or, If only 33% of the healing peptides diffuse back out the depot the right direction, 1 mg/year. 5 years is 5 milligrams of electrophoretically installed drug, and 10 years is 10 mg of iontophoretically installed drug.
How dose potent (strong) can a would healing drug be? there are RNA that heal wounds, and peptides. Some peptides Like GHK-Cu effecting rat behavior to reduce anxiety are biologically active at 500 picogram/Kg doses,which is encouraging, as Genital and Anal mucousa seem to be in the 100 picogram/24 hour range of mass.
This is a public domain Idea
Treon Verdery 12/28/20