h a l f b a k e r yIt's as much a hovercraft as a pancake is a waffle.
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This artificial organ would use the Cori cycle to metabolize Lactic acid from one's muscles. They would be grown in batches from skin-derived stem cells and a piece of the patient's own liver. Then they would be installed (injected?) directly beside all the muscles of the body wherever they may fit.
Permits
far greater stints of anaerobic respiration. Great athletic feats! New world records!
Injectable “satellite livers” could offer an alternative to liver transplantation
https://news.mit.ed...ransplantation-0303
In this study, the mini livers were injected into the fat tissue in the belly. In the future, similar grafts could be delivered to other sites in the body, such as into the spleen or near the kidneys. As long as they have enough space and access to blood vessels, the injected hepatocytes can function similarly to hepatocytes in the liver. [Voice, Mar 05 2026]
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I like the idea. You could keep some in the freezer for injection after a night of far too much alcohol. |
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By the way, what would happen if you had little livers everywhere, and they weren't connected with anything? cancer? |
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I'm not sure, but I'd always thought that
lactic acid stayed pretty close to where it
was made, and was oxidised in situ (within
the muscle cell) rather than being shipped
out to the liver (hence, only the
overworked muscles experience "burn"
after exertion). But maybe I'm wrong? |
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1. Growing new livers from skin
derived stem cells is magic. If this
could be done, people who had bad
livers could just grow themselves new
ones instead of hoping for transplant. |
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2. The muscles themselves do most of
the work metabolizing lactic acid. If
you go anaerobic enough to raise blood
levels other muscles have at the lactic
acid. Lactic acid is good food. |
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I plan to plant lillies in mine. |
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