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Biopoints of Failure

Just like JWST (James Webb Space Telescope) teams enumerated all possible signle-points-of-failure to compute spacecraft risk, enumerate all human organism (or bio-organism) points of failure, and strategize to reduce its failure risk.
  [vote for,

It may be not so hard to start optimizing human organism for longevity as it seems -- simply start making a list of possible bio-organism points of failure to systematically eliminate with redundancies. This could start as a free web wiki ( say, smth like http://points.of.failure.bio ), where are elaborated on.

[failure] - meaning "brain-death or incapacitation" -- as long as brain can function socially productively, consider one not brain-dead.

Mindey, Dec 29 2021

CDC - Death Certs data https://www.cdc.gov...italstatsonline.htm
[Mindey, Dec 30 2021]

FIC - Family of International Classifications https://www.who.int...rds/classifications
Contains: ICD-11, ICF, ICHI - big lists of issues, but not critical points of failure. [Mindey, Dec 30 2021]

failure.bio https://failure.bio
A gist of what I mean: both a "lets..." and a "list..." but yet, I need to check, if there's something like that out there. Maybe should do it on Wikipedia? Could do this on Wikipedia, but it is not as easy to arange and move things around in there. [Mindey, Dec 30 2021]


       List everything that could break and keep spare parts available?   

       [-] Needs better explanation of how, less wishful thinking.
a1, Dec 29 2021

       How will redundancy help with your telomeres?
pertinax, Dec 29 2021

       // Needs better explanation of how, less wishful thinking.   

       [a1], give me an hour, I'll try to explain more specifically, what I mean.
Mindey, Dec 30 2021

       Does "failure" here mean specifically death, or does it include anything going wrong? If it means death, then you could start with the causes of death on death certificates; that would give you a list, quickly, and some statistics for the purposes of prioritization.
pertinax, Dec 30 2021

       [failure] - let's consider it to mean "brain-death or incapacitation" -- as long as brain can function socially productively, consider one not brain- dead. In fact, this removes a swathe of IDC-11 table, essentially, requiring only blood with taking metabolites, providing nutrients and synthesizing antibodies.   

       // If it means death, then you could start with the causes of death on death certificates   

       I had in fact started with that, a publicly available list (death certs, see link)
Mindey, Dec 30 2021

       [a1], check the link ( failure.bio ), it's not a "let's all ...", because it's not something that people are already really doing.   

       It provides a little bit new regarding the focus of these "bio-failures". I just don't know a better (more convenient) way to keep a list of such an important thing, and involve others, like doctors, etc. to contribute.
Mindey, Dec 30 2021

       Still not seeing anything new there. You made a broad, not very specific list of things already defined elsewhere in many other forms.   

       Here’s an example - “Aortic dissection” - a major artery spontaneously fails. Victims often dead before they hit the ground. Tell me how you’ll eliminate potential failure. Have everyone keep a spare aorta in their backpack?   

       If you don’t like that example, give me one of your own: ANY specific point of failure and a strategy to eliminate it - with or without redundancy.
a1, Dec 30 2021

       "Chilton's Guide to the Human Body, for models produced between 1973 and 1976, containing D141A, E143A, A485L mutations on 9°N polymerase."   

       I imagine this could take some time.
RayfordSteele, Dec 30 2021

       // Chilton's Guide ... could take some time //   

       Good point but that's not all I see wrong with [mindey]'s concept. They compare it to designing the JWST. If you're designing from a blank sheet you can look at every part and modify each for reliability. Very different from writing a maintenance and repair manual for a car - or human - after it's been delivered.
a1, Dec 30 2021

       Regarding "Aortic dissection", there are probably (I'm not a doctor...) supplements or proteins that will strengthen aorta walls, reducing the risk of them spontaneously failing. That sort of thing.
neutrinos_shadow, Dec 30 2021


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