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Gastric Botox Therapy

Partial, temporary stomach paralysis for the treatment of morbid obesity
 
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Stomach bypass surgery is increasingly popular as a treatment for morbid obesity, in part because it is the only surgical procedure proven to cause weigh loss in extremely obese people. There are many downsides. One is that the post-operative patient must adhere to an exceptionally restricted diet, with serious complications if he or she does not. Also, the procedure is major surgery, possibly not appropriate for patients in poor health; and reversal of the procedure also requires major surgery. Most serious, the mortality rate is about one patient out of 200.

As an alternative I propose Gastric Botox Therapy, wherein small doses of botulism toxin are used to partially paralyze the muscles of the stomach. The injections are carried out endoscopically through the esophagus. Each treatment is effective for about one month, so repeated treatments are necessary. However, this allows the amount of paralysis to be scaled to the patients indicated weight-loss rate, and it make possible cessation of the treatment without surgery.

The partially-paralyzed stomach will have much-reduced capacity for digesting food, forcing the patient to eat less and to lose weight as a consequence.

Note that Gastric Botox Therapy is not intended for normal weight loss. Like stomach bypass surgery, it is only appropriate for patients who are extremely obese and are at serious risk secondary morbidity or death as a result.

AO, Apr 08 2004

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       This would not work since stomach muscles aid in digestion. Botox would relax these muscles probably just making people sick...
futurebird, Apr 08 2004
  

       Botoxed jaw muscles would slow you down, also.
FarmerJohn, Apr 08 2004
  

       Really uncomfortable braces or canker sores would be effective, too.
phundug, Apr 08 2004
  

       This would turn your stomach into a big flaccid bag. Not at all like stomach stapling. And not that there is anything wrong with big flaccid bags.
bungston, Apr 08 2004
  

       Certainly an easier procedure than stapling. If the Botox slows down the stomach so the food stays longer in the stomach this could work nicely.   

       [bungston] It would make the stomach a big bag, but when the bag is full its full and the person can't eat any more until the food has moved on.
kbecker, Apr 08 2004
  

       I question the sanity of a person who willingly has botulism toxin injected directly into their digestive system, or any body part actually.
whatastrangeperson, Apr 09 2004
  

       Paralyze your urinary sphincter -- then get up and make another trip to the buffet. I dare you.
dpsyplc, Apr 10 2004
  

       botox + stomach = <Mr. Creosole>Bring me a bucket!</Mr. Creosole>
thumbwax, Apr 10 2004
  
      
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